How IPF
Progresses

Home Learn About IPF How IPF Progresses

Understanding idiopathic pulmonary fibrosis (IPF) progression is key when it comes to making treatment decisions.

This section can help—scroll down to learn about IPF progression and why slowing it down with treatment is important.

what is
ipf progression?

IPF is a progressive disease, which means it will worsen over time. It is difficult to know how quickly IPF will progress. Some patients progress rapidly while others progress slowly or remain the same for long periods.

HOW DOES TREATMENT
AFFECT PROGRESSION?

When IPF is progressing slowly, it may not noticeably affect lung function for some time, meaning a person with IPF may not see or feel the effects of progression. It’s important to remember that IPF is still a progressive disease. If left untreated, IPF may worsen more quickly than if the patient were on treatment. That’s why getting on treatment is important to help slow disease progression.

Be sure to ask your doctor if treating with OFEV® (nintedanib) could be the right next step for you.

Take a deeper dive into IPF progression by watching this video.

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  • IPF is a serious and progressive lung disease that may impact both lungs and worsens over time, causing irreversible and permanent damage. Healthy lungs work by expanding to take in oxygen, which then travels through your bloodstream to your entire body.

  • IPF affects the lungs, causing them to lose the ability to expand fully and therefore take in less oxygen, which causes shortness of breath. Everyone experiences decline in lung function as they age, but patients with IPF lose lung function at a rate of 3 to 4 times more.

  • Some patients experience a severe and sudden worsening of their symptoms called an acute exacerbation. These events can leave patients with less lung function and is a possible sign that IPF is getting worse.

  • OFEV is an FDA-approved medicine that helps slow lung function decline in patients with IPF. In 3 out of 3 medical studies, taking OFEV slowed the decline in lung function by approximately 50%. In 2 out of 3 medical studies, OFEV significantly reduced the risk of a first acute exacerbation.

Find more info on how OFEV may help slow IPF progression.

SEE HOW OFEV CAN HELP

what are
acute exacerbations?

An acute exacerbation is a serious and sudden worsening of symptoms associated with accelerated disease progression. Here’s what you need to know about acute exacerbations:

  • They can occur at any point during disease progression
  • They can sometimes be the first indicator of IPF
  • The cause is unknown
IPF disease progression graph IPF disease progression graph

Reprinted with permission of the American Thoracic Society. Copyright © 2018 American Thoracic Society. Raghu et al. 2011. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med. 183:788-824. The American Journal of Respiratory and Critical Care Medicine is an official journal of the American Thoracic Society.

Quick Fact: 1 in 4 people with IPF may suffer an acute exacerbation over a 3-year period.

See how OFEV may help reduce the risk of an acute exacerbation.

READ ABOUT OFEV HERE

SLOW THE PATH
OF IPF PROGRESSION

Slowing the rate of lung function decline and reducing the risk of an acute exacerbation are important when it comes to treating IPF. OFEV may help with both.

This twice-daily pill may help your lung function by slowing the progression of IPF and may help reduce the chance of having an acute exacerbation.

Work with your doctor to discuss treatment options. Start treatment so you may start slowing IPF progression.

“From our research, we knew that IPF would progress and that it could be very quick. We have too many things that we’re enjoying in life, so we wanted to do something to help slow the progression of his IPF. ”

Susan, OFEV Mentor, Wife of Someone with IPF

Susan, OFEV Mentor, Wife of Someone with IPF

Susan, OFEV Mentor, Wife of Someone with IPF