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How OFEV Can Help

As of now, there is no cure for idiopathic pulmonary fibrosis (IPF). However, there
is an IPF treatment called OFEV® (nintedanib).

OFEV may help slow your ipf progression

In 3 out of 3 medical studies, OFEV capsules were proven to slow the decline in lung function by about 50%. This was determined by testing a patient's forced vital capacity, or FVC, after 1 year of therapy. FVC measurement is one of the ways the progression
of IPF is measured.

OFEV reduces serious attacks of
shortness of breath

Lung function declines at different rates in different people. Some may progress rapidly while others may remain the same for long periods of time. Some people may experience "acute exacerbations." These attacks are a sudden and often permanent worsening of the disease. They can have many causes. Your healthcare team will determine if the episode is caused by IPF.

OFEV patients were 80% less likely
to have an
acute exacerbation

The chance of having an acute exacerbation during a 1-year period was significantly reduced in patients taking OFEV compared with those taking placebo in 2 out of 3 medical studies.

In a medical study, OFEV patients were 80% less likely to have an acute exacerbation versus placebo patients (7.3% vs 1.5%, respectively, with an absolute difference of 5.8%).

The 2 trials showing a benefit had similar results. The remaining trial showed no effect of OFEV on acute exacerbations.

How OFEV works

OFEV is a prescription medicine designed to work for people with IPF by blocking the effects of some of the substances that are involved in the scarring of the lungs.

Talk to your doctor to see if OFEV is right for you.

What is the most important information
I should know about OFEV?

OFEV can cause harm, birth defects or death to an unborn baby. Women should not become pregnant while taking OFEV. Women who are able to become pregnant should have a pregnancy test before starting treatment and should use birth control during and for at least 3 months after your last dose. If you become pregnant while taking OFEV, tell your doctor right away.

OFEV proven to slow progression of IPF by about 50%
OFEV® (nintedanib) Package

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