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What to Talk to Your Doctor About and What Are the Possible Side Effects of OFEV?
What should I tell my doctor before
using OFEV?

Before you take OFEV® (nintedanib), tell your doctor if you have liver problems, heart problems, a history of blood clots, a bleeding problem or a family history of a bleeding problem, had recent surgery in your stomach (abdominal) area, are a smoker, or have any other medical conditions.

Tell your doctor if you are pregnant or plan to become pregnant. You should avoid becoming pregnant while taking OFEV capsules. OFEV can cause harm, birth defects, or death to an unborn baby. Use appropriate birth control methods while taking OFEV and for at least 3 months after your last dose.

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if OFEV passes into your breast milk. You should not breastfeed while
taking OFEV.

Tell your doctor if you currently smoke. You should stop smoking prior to taking OFEV and avoid smoking
during treatment.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements such as St. John’s wort. Keep a list of the medicines you take and show it to your doctor and pharmacist when you get a new medicine.

What are the possible side effects
of OFEV?

OFEV may cause serious side effects.
TELL YOUR DOCTOR RIGHT AWAY if
you are experiencing any side effects, including:

The most common side effects of OFEV are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.

These are not all the possible side effects of OFEV. For more information, ask your doctor or pharmacist.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit https://www.fda.gov/Safety/MedWatch/default.htm or call 1-800-FDA-1088.

Keep a record of how
you are feeling

Often, it is hard to remember how you feel from one day to another. For this reason, it is important to keep track of your health every day, including any side effects you may experience. You can do this by writing all of your experiences in your journal. You will have a record that you can show to your doctor during your regular visits. In this way, you can work together to address any concerns you may have during treatment with OFEV.

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